Normalizes a raw counts matrix into log transformed counts per millions using the edgeR 'Trimmed Mean of M-Values' (TMM) normalization method. For more information please refer to the edgeR package (https://bioconductor.org/packages/release/bioc/html/edgeR.html).
countsToTmm(counts, log = TRUE, prior.count = 3)
counts | The matrix of counts. |
---|---|
log | Passed to cpm. |
prior.count | Passed to cpm. |
The normalized expression matrix